Neutralization Antibody

Tsanangudzo Pfupi:

SARS-CoV-2 hutachiona hweRNA hwakaputirwa uye humwechete.1ts genome RNA inoisa puroteni isingaite uye akati wandei mapuroteni, anosanganisira spike(s), envelope(E), membrane(M) uye nucleocapsid(N) mapuroteni.

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Pathogenesis:

Iprotein yeS ndiyo inokonzera kusungirirwa kwehutachiona uye kupinda mumaseru ekugamuchira, ayo ane zvikamu zviviri zvinoshanda, s1 uye s2 uye receptor binding domain (RBD) iri mukati me s1 subunits. Iyo RBD yeSARS-CoV-2 S protein inopindirana. ine host angiotensin inoshandura enzyme 2 (AcE2), ichikonzera shanduko yekuchinja mune s2 subunit inoguma.

mukusanganiswa kwevhairasi uye kupinda musero rinotarisirwa .Maprotease akavanzika emunhu, akadai seTMPRss2 nefurin, anogara kune mavirally.target cells.

Aya maprotease anowedzera hutachiona kupinda mumasero anotambira kuburikidza neproteolysis yeese ari maviri s1, s2, uye AcE2 mapuroteni.

Inoshandiswa kushandiswa:

Iyo Anti SARS-CoV-2 Neutralizing Antibody Rapid Test Kit inogadzirwa kuti in vitro qualitative kuonekwa kweSARS-CoV-2 neutralizing masoja ekudzivirira chirwere mumasampuli eropa revanhu.SARS-CoV-2 Neutralizing antibody chiratidzo chakakosha chekuongorora kushanda kweiyo SARS-CoV-2 vaccine.Iyo reagent ndeyekubvisa masoja ekudzivirira chirwere mumienzaniso kubva kuvanhu mushure mejekiseni rejekiseni kana kupora kubva kucoV1D.19.Kiti iyi ichabatsirawo pakuongorora kwazvino kwecoV1D.19 kwesero-prevalence, ongororo yekudzivirira mombe, kurarama kwenguva refu kwedziviriro yekudzivirira, kushanda nesimba kwevari kutsvaga majekiseni akasiyana pamwe nekuronda utachiona mumhuka.

kuchengetedza mamiriro uye Kushanda:

Mareagents ese akagadzirira kushandiswa sekupihwa.Zvisina kuvhurwa reagent kits dzakagadzikana pa4"c ～30"c kwemwedzi makumi maviri nemana.1t inofanira kushandiswa mukati meawa imwe kana homwe yavhurwa.Usaomesa kiti kana kufumura kit iri pamusoro pe37"c panguva yekuchengetedza.

Tsanangudzo:

1 bvunzo / bhokisi;5 miedzo / bhokisi;25 bvunzo / bhokisi;50 bvunzo / bhokisi.

Test Procedure:

Usavhura homwe kusvika wagadzirira kuita bvunzo, uye iyo single.use test inokurudzirwa kuti ishandiswe pasi pekunyorova kwenzvimbo (RHs70%) mukati meawa imwe.

1.Bvumira zvikamu zvese zvekiti uye zvienzaniso kusvika mukamuri tembiricha pakati pe18"c～26"c isati yaedzwa.2.Bvisa kadhi rekuedza kubva muhomwe yefoil uye uise panzvimbo yakachena yakaoma.

3.1 ratidza kadhi rebvunzo remuenzaniso wega wega.

4.Shandisa dropper kuti upe donho rimwe chete (1) ye serum, plasma kana sampuli yeropa rose (40uL) mumucherechedzo zvakanaka pane kadhi rekuedza, rinoteverwa nedonho rimwe remuenzaniso bufer.

5.tanga timer uye verenga mhedzisiro mumaminitsi gumi nemashanu.

Tsanangudzo yeMbairo Yekuedza:

1 dudzira mhedzisiro yebvunzo zvinoenderana neinotevera ruvara chati (SePazasi).

1.1f kusimba kweruvara kwakadzikira pane G4, zvichiratidza kuwanda kwekudzivirira masoja ekudzivirira chirwere akakurisa kupfuura 200 PRNT50 2.1f kusimba kweruvara kuri pakati peG4 neG6, zvichiratidza kuwanda kwekudzivirira masoja ekudzivirira chirwere kunosvika 100 PRNT50 3.1f kusimba kweruvara kuri pedyo neG7 , zvichiratidza kuti kunyura ndekwekutambisa masoja ekudzivirira chirwere i50 PRNT50

4.Muganho wekuona ndeye 50 PRNT50

5.f kusimba kwemavara kune simba kupfuura G7, ratidza mhedzisiro yakaipa.

Zvakapfuura: Automatic Digital Wrist Blood Pressure Monitor

Zvinotevera: Bhurocha-PocRoc®SARS-CoV-2 Antigen Rapid Test K0429